Signs of Alzheimer’s Seen 18 Years Before Symptoms

The results of a study from Rush University Medical Center in Chicago show that signs of cognitive impairment can be detected as early as 18 years before the disease is diagnosed.Signs of Alzheimer's Seen 18 Years Before Symptoms

Learn more about this study and what it means for early detection of dementia.

Signs of Alzheimer’s Seen Years Before Diagnosis

A research team led by associate professor of internal medicine at Rush University, Kumar Rajan, has found that early signs of cognitive impairment leading to Alzheimer’s may present themselves 18 years before symptoms occur.

Rajan and his colleagues observed over 2,000 seniors who did not have dementia over the span of 18 years. Every three years, the participants took a mental skills test and then analyzed the results over time. They found that those seniors who eventually developed Alzheimer’s has lower test scores throughout the 18 year period. In addition, their scores actually declined with each test.

Researchers concluded that for each unit their score dropped, the risk of developing Alzheimer’s increased by 85%.

Testing to Predict Alzheimer’s Risk

Researchers caution that their study only demonstrates a link between testing scores and a group-level risk and that as of now, the tests can not be used to predict an individual’s risk of developing Alzheimer’s. More research will be needed to determine how testing can be used to determine an individual’s risk.

For now, researchers believe their findings suggest that a cognitive test should be part of a regular assessment for people beginning in middle age. Catching Alzheimer’s early will give doctors more time to intervene and slow the progression of the disease.

Next, Rajan plans to study the effects of brain-stimulating activities on Alzheimer’s once it is diagnosed.

Do you think regular cognitive testing should be a part of standard medical care? Why or why not? Share your thoughts with us in the comments below.

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Please leave your thoughts and comments

  • Kathaleen Stapleford

    There should be screening right around 45 and up . Brain health is just as important as body health if not more .

    • Janice Cady

      I hear this and yet wonder, why? Do we want to know 18 years ahead of this horrible diagnosis? I sure know that I don’t want to know. When the time comes that there is a cure or even a way to really delay it, theñ yes I would want to know. Until then, let me enjoy my good years without knowing what horror lies ahead.

      • Johnandkat Stapleford

        There are medication you can take to delay the effects of Alzheimer’s. I personally know that there are hereditary early onset cases that could have been treated if we had only known . my mother in law a sweet woman was diagnosed at 55 and it was already progressed . they are making strides in treatment and therapies . and there is so much more information gained from the state (onset)

    • Linda Silkwood


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